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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '36c3f664288b5a473a2d513e3e7d05e1565d665a86fe51a30142d26950428a23' 
  AND token = 'RgcSM6ynJ9MiCTBRdFCCNMVt+oPqLSf9UKDd4VgcDX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}