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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fd466780cf985a83917814b4fbd287ceb62ec952f569540ddf0f171ca4234100' 
  AND token = '2PFOavRSyte01pPmDfwT7CZvpuZnCpnfTi78We1ucwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}