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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5d498ab429aaf0dcb5deedb75d596e0717879eebed7726bd43cd95ddb575fb9f' 
  AND token = 'jFYMZ7GtXeTk106L7JNVIIOX42O+o8a7UQSIHnBhZR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}