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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b80a1931d03afdc6d7d5d92fa6ff3ae9066a434d7ec09167b5aa33bc140e6d11' 
  AND token = 'QHs20FUFi8Qr1a+o6FjjCw+wOZU+pHGjS7wokmOHy/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}