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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '099eac833132cdbaf5822c13fb8e2635a2586e0fbd0c7e0e6246667145d8e7a8' 
  AND token = 'y48ADp075fyffUXpv3hWvcotMi6gVVL1IeXSCyXJWz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}