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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e48eb8e26899444447b7ab18c2654cf4762bdd7df7e1882e79753822ca0f645' 
  AND token = 'RJ+8we50bwHqQTN1ygJLe3Q4jk+K1cELIyKEZLSgG0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}