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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4881f427437147cb3b5b045b8a565bc90ea9115d7e2e9ba89bc7ae43b7fbcb85' 
  AND token = 'VLO6rNNWGbDirLOvEtzNQPFIm1GzAdNilZVVcOLVxjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}