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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '375516cff5f80b5c18e59c5475c76cc6ae3d086087bbc3a6041e4fbbf2956e8d' 
  AND token = '/flndEd1nW5JDq47PKIdm+2ESGen/55xk71sVQpBGTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}