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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8728676bc8d8ae0d9dee36bc7571011d29c1fbf58cbdde1fe4ad3af9c8bd350b' 
  AND token = '2s5Libhb2b0LQ8gRCIPFwr7a4cvpyCyvUU8N4NLVd88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}