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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2bdef0715ea3acb41c7b4152475b72311ee0981d1fdeb368811a0f9e9a37038' 
  AND token = 'PA4uwO3FTN/AW0UFR3rWAVxHWa6dcfnG3FnrHYfb3Ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}