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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66ed1a3863e728a3002df00e63f71c00aaa7a13b4490eb119f31514f79bdaa91' 
  AND token = 'diVK64DbL2lLB+ZvoHQrb8RzT7HH8WP6LOZrVEp2+Xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}