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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '458676d4c1ecd2fd4cff66cc7571561c0d12f49b71baf6982a365d50527ec62a' 
  AND token = 'HIrsh6fc6G8A5OeFFQ3Mz98ddAT2nc8MstJqeEuA2SI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}