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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8c77f8b1133658e80c8ca251b09ce804143c6d10e3872c0c2ca5b832300d9078' 
  AND token = '4TOnCTnYAqvHDRNBw0DC4wfdFSrgl0BDxMZc0YD6/gA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}