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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25bb29c3ca22ea73378ae957b99b56390c972e201ec5e9cf74a6f2abc9fdbe5d' 
  AND token = 'A14FndVMS28HvQYyQIEWpemF+pT9KEF9oGqmJKSbq9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}