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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6a1580189af69e200329094d555b8c0d97e130a03bb79c84711a3aa020c60712' 
  AND token = 'R4Fh8XQxIT6l6ix3qftkTNy5gbCapTcChvp8vC4ka2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}