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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0ed113ec23bfac40e6abc47ec0f29de10b0ce42e1d14974ddd865f0b3086cb52' 
  AND token = 'jScL7vCd+N7CsMdNFeBjUy6ujqoOLlcOHksP05kE9us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}