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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ec46dd6cb53049f906bb3646e866f45dffc9c66b82f304467aeaa56d00e5e730' 
  AND token = 'Fxs7Boyo/MiHDxMr9rjy+BqINhOvhqVEVqP7xLj0+FU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}