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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4199c7f53b05b6de5c47bf6758e5912700630870c86c89cc321fc0eb7bbbf0ba' 
  AND token = '4LOxXjt8X+jXtQIJN4V1uJM8Zf8cFEcG4GTtypk3nOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}