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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd9b6b2a2171a7bedc102f3abc6602fdafb293d57a24877de6e8641cc3c22302d' 
  AND token = 'MiUQ7wH+s4UfAtOt2n1sGsDa2N/lSQyFEeQxMkAOMWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}