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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'edc38405b43e9c4f48001c81352cc2191e510408cddd5bd001e5e7aceb3b80fa' 
  AND token = 'oEK2/tJN7NdwO5CBOW2Cr3AAt0pDbCKAvbTpgziZCKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}