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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8b816764ec2fe7dbde0dc9b033e024338e553cf7af061bee520acd1a538ce6c0' 
  AND token = 'BHBGDaqIZurfIpxyQuNBCt9PTDVd77+CzaSZ19VrOos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}