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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2d1a4eb1f84cd58cca0f178fc091f5c6cdcd280ef591830c3b53353018a6a298' 
  AND token = 'GiTV0RMajHYotOOz9iC2QDKCxJtiJgwX2HWPMueCAc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}