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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6480e7be16e5ad0393235550653a6e3df49eb6fce753cc1d59624555a6e24dce' 
  AND token = 'aTab5F6bNVA4HW0w0VECa7wl81KRW8CKAgihDJp7ZTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}