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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b1bd28c9f4e138e296b1bb45c39c3a8073d78a0df5fba58360a0f3c4810a87aa' 
  AND token = 'WSGORYaDZL2EWYS+mckeixsDf6l5MNDlO/F693snCCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}