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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2b607aa16d4c2628be6316541b3a34334e0bc6a2e01fd78a104233dabc4e525' 
  AND token = 'mEoK99lFy4LOeW0u0Ru/RadFV4rJX/Zl/UWqixjJFkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}