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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5711fdf39c7b095e84fe0f4dabdc5e025615e8cdcb3809c0ee6ece6026760608' 
  AND token = 'R19Y4JadQyWHKrsd6QAE4rItNYwIWL6OJhwTRoHA9GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}