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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '59a85c08ebaa5d2c0a16d1eb9dae438295f146a7b8d1a10b6c8fc96527886db0' 
  AND token = '/T31v/vWzREnGRG2wpblpVymVsQaEg8lz1yXVQM6Ito=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}