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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3195e36690ae3adf82f6904a6afadc195778712af9d3c76c96c8f28402d1da3d' 
  AND token = 'x/zsouh2i1JOkN2yrU3lljDhhNAmCQTi72S6GaCn7Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}