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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e09fd870dfa59b17b8325f3e601a7b7a1a1ab4588b1382cbeeeee17af39b9077' 
  AND token = '0PzXkDImtlzMNrW4iHDaHGaEtLjUHMKK8W40HIEhANw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}