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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd7c0e4d761992c08d3652c3d59622822fc9ddbfdb7994c5221c9bbe41f7f0185' 
  AND token = 'VHrMMQ61KXTPo5YK9/XUOv/Hibx4f0Yr3Y901tL9y70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}