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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b4290de22d40b013af104c48bacb48db13159675405c486c1e7e382a28f42087' 
  AND token = 'pyECsWW5tFsrnjhZxMCIpE2+vkLZtpevcX/frB2yLbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}