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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c00687b289bcc470e4e38c6418a255e906cc2a4dc2534b62cb497666da84ea99' 
  AND token = 'JmzhYqjmE1mcqPEVSwi6OGHxOyGmHr6Ygr55ngXVcFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}