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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a53ea8a90733c4522f3c0513b80dd9dbadd34b7111bf3698cedba125ad7516bf' 
  AND token = '51Qfamj0FOLNnFoJ1q9iqGP5uBlAR1lnU/fQB+DPcdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}