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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '58d88f7c88bebc01ead2c8c8da0555f4a05001d08b37d77a0f000782f540927a' 
  AND token = 'L4tzZGBVeU6TH2EGyKoZTVLWNkyUgLQlu1JTb+lTqM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}