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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '439f342a73e4a428f509a44778e397ea88450d260591769248eacd502a522193' 
  AND token = 'p225APMXtGVHOFr8flvNWTUGaqHEx+3DmPhT6KSeIAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}