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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e8361e05a6c41e0840f82264d528ba23fdaf3c1cf5620dc8bea1bc375f721815' 
  AND token = 'JiOnXg13gnTRM8sMbbX9tOL6aovXQp0jRsdnNdYre+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}