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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e4d227d1c46cfab709476651abb5e3b88ee69c4d084a06b068e575b8f33bbb6' 
  AND token = 'IidrGOsRMtTNmF/M76aXWSQURVH3N7SyOLN9h43WSi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}