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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65001ebb8487701d2e0074e5735d18c1306ca2a01b057db6ba24a148bbf3fbc1' 
  AND token = 'qBv9tnwbqIniI46TmfOw5q/4ZZcn7XJh2pqVXM47WK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}