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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8cd5e0ce8fff0e4c92703ed9d53622258849aa61a22050975f6f3068b8fee6b3' 
  AND token = 'iayj3HSTyyTGCDpDsZAjpOvWd2cTKwAsS6tp8n0VWqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}