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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2f85081d54cbd113de6a3ef71c5ce2ad74bf370840f1c011f4595ce5fe2c221a' 
  AND token = '6ysk0PfavcafAAz/07u7FAADVVIcP2D5k7RFkDAyfOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}