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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '053d1034be60e525c672b44a5fe3fd58f0572e4b5f0abe659a6ae1a5200e4a72' 
  AND token = 'eqG6VYfKUe3WpCBwjdykmsQ4hyT1BK/6YWyNvhDlWB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}