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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dede18f959759002982f75bcd3cac0ecb1d8d2667880bae9979cd71ccfa4f7f9' 
  AND token = '+vCqkwTVsO7cwWWmRltQOXoqkEbnIqYGKZkHGyMy1lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}