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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5efeadc0004ffe1c3d698d2d2146d84b4d170488200f153099dc3aab7a1e2c65' 
  AND token = 'eD1iMIbuZjdrjH0mjbyK9E/h8F0GmYS7++eh/P7lSJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}