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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c0e9a54d63952cf367e0ad8a7b74e625f227bb4cd7793c69d2abbd535190f4c7' 
  AND token = 'TqECTNvwAB9clMA6XaTMpu2ENN7lQKpE/C3rQHrhExY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}