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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '52779c750d52c771c5a511fca33607ff2a51201687f7aa505820145c7e85d2ee' 
  AND token = 'jNjOHtGvgCcRAZvb0csxDoT18KekSntbVd++w/HfeOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}