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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8189f83331f0ceed38ee11753db68e72d90dd449e185919bb6816e2639bc3a09' 
  AND token = 'd0lI7b0v57gccpALE/vrnbs5ZOA2cYbLOo2DSaGvFqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}