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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a438ca227df7a306b620f78ed28a0fc4b5442919117ff0596cd0fa11a22e0b88' 
  AND token = '1CuiFWqAA0QnV9+O9vIBdPmPDuo2RH30+LleORZ5ZQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}