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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '281a5152f876c16a8f2e94cbefbf88f735f9c5c3513f66fb06620cb4ba7701f0' 
  AND token = 'kn3fQU41ViwRC0kkSkHOLvtS3Wxrm9twTJdSrdf6xNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}