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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0df972d6d5e733c96473a4fc17efdc33eab327fe50364ccee61c72ea243d7dd6' 
  AND token = 'e6qxFQ9TfuGrsMFCxUfU9wwY284K0OKZ0bDGE1yLw5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}