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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a8baf00192d28d9e5517690b0e8eed7f37da3d4348a423e1767138b19d586446' 
  AND token = 'd65qZEiosY/PYpGtMe0EyuHV24MPnIadERsQI+ZtTZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}